Tetralogy of Fallot (TOF)

Tetralogy of Fallot is a rare but serious congenital heart defect present at birth, disrupting normal blood flow through the heart. It results in oxygen-poor blood circulating through the body, often leading to symptoms like cyanosis (a bluish skin tint), fatigue, difficulty breathing if left untreated.
The condition involves four distinct heart abnormalities: Ventricular Septal Defect (VSD): A hole between the heart’s lower chambers, Pulmonary Stenosis: Narrowing of the pathway from the right ventricle to the lungs, Overriding Aorta: The aorta sits over the VSD, receiving blood from both ventricles, Right Ventricular Hypertrophy (RVH): Thickening of the right ventricle’s muscle wall due to overwork, The precise causes are often unknown, but contributing factors include genetics, maternal infections like rubella, alcohol consumption during pregnancy, other environmental influences. Early diagnosis through fetal echocardiography or newborn screenings is crucial for timely intervention.
Surgical correction remains the stard treatment, often performed in infancy. With successful surgery regular cardiology follow-ups, most patients go on to live full, active lives.
Cost: Starts from USD 5600–6000 depending on the complexity hospital.

The diagnosis usually begins with a physical examination, where a doctor may detect a heart murmur—often the first clue. After the initial check-up, the following tests are typically conducted: Echocardiogram (ECHO): This ultrasound of the heart is the primary tool to visualise the structure of the heart, identify the four defects, assess blood flow, Electrocardiogram (ECG): Measures the heart’s electrical activity to detect abnormal rhythms enlargement of the right ventricle, Chest X-ray: Helps to view the size shape of the heart check for the characteristic "boot-shaped" heart associated with Tetralogy of Fallot, Pulse Oximetry: A simple, non-invasive test to measure the oxygen level in the blood, which is often lower in these patients, Cardiac MRI or CT Scan: Provides detailed images of the heart to assist in surgical planning, Cardiac Catheterisation (in some cases): Invasive test used to measure pressures in the heart chambers blood vessels, get additional structural details if needed. Early diagnosis, often shortly after birth, allows for timely surgical intervention, improving long-term outcomes.
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